Road Trip to Boston

CD44's nuclear road trip

The downside of microtubule stability S talled microtubules might be responsible for some cases of the neurological disorder Charcot-Marie-Tooth (CMT) disease, Tanabe and Takei report. A mutant protein makes the microtubules too stable to perform their jobs, the researchers fi nd. The mutations behind CMT disease slow nerve impulses, reduce their strength, or both. One of these mutations leads ...

Medicaid in 2006: a trip down the yellow brick road.

This issue brief explores the continuing evolution of the Medicaid program on several fronts. It discusses the benefits and cost-sharing flexibility that is included in the Deficit Reduction Act of 2005 (DRA) and examines the implications of these provisions for states, beneficiaries, and providers. The paper also explores recent trends in section 1115 waiver development and considers the use o...

Tip growth in filamentous fungi: a road trip to the apex.

Fungal hyphae extend by apical growth. This process involves the polarized traffic of secretory vesicles to the Spitzenkörper (SPK) and their subsequent distribution to specific domains of the plasma membrane, where they fuse to provide all the enzymes and material needed for cell wall expansion. Endocytic recycling and localized translation of specific mRNAs play an important role in hyphal ap...

Field trip to

I/S Nordforbrænding is an inter-municipal waste management company located north of Copenhagen, the capital of Denmark, which serves approximately 180,000 inhabitants. It was founded in 1965 and it is owned by six municipalities in North Sealand: Allerød, Søllerød, Hørsholm, Fredensborg-Humlebæk, Karlebo and Helsingør as shown in Fig. 1. The company’s mission was to establish a Waste-to-Energy ...

Osler came to Boston.